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ONTOLOGY REPORT - ANNOTATIONS

Term:delta24-sterol reductase activity
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Accession:GO:0050614 term browser browse the term
Definition:Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.
Synonyms:exact_synonym: D24-sterol reductase activity
 narrow_synonym: lanosterol Delta(24)-reductase activity
 related_synonym: lanosterol delta24-reductase activity;   sterol:NADP+ delta24-oxidoreductase activity
 xref: EC:1.3.1.72;   MetaCyc:RXN66-321;   RHEA:13685;   Reactome:R-HSA-9755937 "DHCR24 reduces LAN to 24,25-dhLAN";   reactome:R-HSA-196417 "Reduction of desmosterol to cholesterol";   reactome:R-HSA-6807064 "DHCR24 reduces ZYMOL to ZYMSTNL"

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delta24-sterol reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase enables IEA UniProt GO_REF:0000003 NCBI chr20:78,052,565...78,088,918
Ensembl chr20:78,052,607...78,086,303 		JBrowse link
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  molecular_function 18050
    catalytic activity 5520
      oxidoreductase activity 718
        oxidoreductase activity, acting on the CH-CH group of donors 55
          oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 26
            delta24-sterol reductase activity 1
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